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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 732955
Species: Mus musculus
CRRD Object: Gene
Symbol: Dusp1
Name: dual specificity phosphatase 1
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:6208976480464CTD[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in decreased expression of DUSP1 mRNA], [Taurine binds to Zinc] which results in increased expression of DUSP1 mRNA, [Taurine binds to Zinc] which results in increased expression of DUSP1 protein

PMID:26335259
multiple interactionsISORGD:7329546480464CTD[PCI 5002 co-treated with Zinc] results in increased expression of DUSP1 mRNA

PMID:18593933
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.