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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 733705
Species: Homo sapiens
CRRD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: CHEBI:17323
Term: trans-pinosylvin
Definition: A pinosylvin that has formula C14H12O2.
Chemical ID: MESH:C049032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA, [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA, [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA, [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA, [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA, [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA, pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein

PMID:23333577
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.