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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 733705
Species: Homo sapiens
CRRD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: CHEBI:42725
Term: 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine
Definition: An imidazoquinoline that is 3H-imidazo[4,5-f]quinoline substituted by a methyl group at position 3 and an amino group at position 2.
Chemical ID: MESH:C029216
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases mutagenesisISORGD:704876480464CTD2-amino-3-methylimidazo(4, 5-f)quinoline results in increased mutagenesis of CTNNB1 gene

PMID:12628520, PMID:9515794
multiple interactionsISORGD:704876480464CTD[chlorophyllin affects the reaction [2-amino-3-methylimidazo(4, 5-f)quinoline results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein], chlorophyllin affects the reaction [2-amino-3-methylimidazo(4, 5-f)quinoline results in increased mutagenesis of CTNNB1 gene]

PMID:12628520
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.