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CRRD ID: 734100
Species: Homo sapiens
CRRD Object: Gene
Symbol: SHANK1
Name: SH3 and multiple ankyrin repeat domains 1
Acc ID: GO:0014069
Term: postsynaptic density
Definition: An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
Definition Source(s): GOC:BHF, GOC:dos, GOC:ef, GOC:jid, GOC:pr, GOC:sjp,, PMID:14532281, Wikipedia:Postsynaptic_density
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0040752, MGI:MGI:3613677, PANTHER:PTN001191880, RGD:628772, RGD:692642290271GO_Central (PMID:21873635)

 ISSUniProtKB:D3YZU12290271BHF-UCL GO_REF:0000024
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.