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GENE - TERM ANNOTATION REPORT

CRRD ID: 734100
Species: Homo sapiens
CRRD Object: Gene
Symbol: SHANK1
Name: SH3 and multiple ankyrin repeat domains 1
Acc ID: GO:0030160
Term: GKAP/Homer scaffold activity
Definition: Functions as a physical support bridging the N-methyl-D-aspartate receptor-PSD-95-GKAP complex and the mGluR-Homer complex, which are involved in receptor signaling in synapses.
Definition Source(s): PMID:10506216
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:3613677, PANTHER:PTN001191878, RGD:621011, RGD:692642290271GO_Central (PMID:21873635)

PMID:21873635
 ISSUniProtKB:D3YZU12290271BHF-UCL GO_REF:0000024
 ISSUniProtKB:Q9WV482290271BHF-UCL GO_REF:0000024
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