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CRRD ID: 734219
Species: Homo sapiens
CRRD Object: Gene
Symbol: ADCY2
Name: adenylate cyclase 2
Acc ID: GO:0007189
Term: adenylate cyclase-activating G protein-coupled receptor signaling pathway
Definition: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:108450, MGI:MGI:87917, MGI:MGI:99673, MGI:MGI:99675, PANTHER:PTN002899368, RGD:2036, RGD:619965, RGD:619966, RGD:71014, UniProtKB:O43306, UniProtKB:O60503, UniProtKB:O95622, UniProtKB:P19754, dictyBase:DDB_G02815452290271GO_Central (PMID:21873635)

 ISSUniProtKB:P267692290271UniProtKB GO_REF:0000024
 TAS 2290271Reactome Reactome:R-HSA-170660
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.