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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737062
Species: Homo sapiens
CRRD Object: Gene
Symbol: PRKCA
Name: protein kinase C alpha
Acc ID: CHEBI:1367
Term: 3,3',4,4'-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at position 3 and 4 on each phenyl group are replaced by chlorines.
Chemical ID: MESH:C028451
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityISORGD:33956480464CTD3, 4, 3', 4'-tetrachlorobiphenyl results in increased activity of PRKCA protein

PMID:16263226
increases expressionISORGD:33956480464CTD3, 4, 3', 4'-tetrachlorobiphenyl results in increased expression of PRKCA protein

PMID:16263226
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.