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GENE - TERM ANNOTATION REPORT

CRRD ID: 8792317
Species: Chinchilla lanigera
CRRD Object: Gene
Symbol: Sfrp5
Name: secreted frizzled related protein 5
Acc ID: GO:0090179
Term: planar cell polarity pathway involved in neural tube closure
Definition: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.
Definition Source(s): GOC:ascb_2009, GOC:dph, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sfrp5 ISOMGI:MGI:892014, MGI:MGI:2135272, MGI:MGI:1080789068941MGI (MGI:MGI:3793375, PMID:18257070)

MGI:MGI:3793375, PMID:18257070
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.