Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

CRRD ID: 9009966
Species: Chinchilla lanigera
CRRD Object: Gene
Symbol: Palb2
Name: partner and localizer of BRCA2
Acc ID: DOID:5683
Term: hereditary breast ovarian cancer syndrome
Definition: Autosomal dominant HEREDITARY CANCER SYNDROME in which a mutation most often in either BRCA1 or BRCA2 is associated with a significantly increased risk for breast and ovarian cancers.
Definition Source(s): MESH:D061325, http://en.wikipedia.org/wiki/Hereditary_breast%E2%80%93ovarian_cancer_syndrome "DO", http://www.cancer.gov/cancertopics/pdq/genetics/breast-and-ovarian/HealthProfessional/page1 "DO", https://www.jax.org/education-and-learning/clinical-and-continuing-education/cancer-resources/hereditary-breast-and-ovarian-cancer-syndrome-factsheet "DO", https://www.ncbi.nlm.nih.gov/books/NBK1247/ "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Palb2 ISORGD:110936329068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:21618343, PMID:24141787, PMID:25741868
Palb2 ISORGD:115600859068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:27067391
Palb2 ISORGD:128848129068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 2

PMID:25741868, PMID:28492532, PMID:30287823
Palb2 ISORGD:134682889068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:28492532
Palb2 ISORGD:134838229068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:28492532
Palb2 ISORGD:135171459068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 1

PMID:23977390, PMID:26250988, PMID:29922827
Palb2 ISORGD:135171609068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

 
Palb2 ISORGD:137050619068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868, PMID:30287823
Palb2 ISORGD:147066849068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868, PMID:30472649, PMID:30552643
Palb2 ISORGD:253242649068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868, PMID:30287823
Palb2 ISORGD:253246609068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868
Palb2 ISORGD:268884599068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868
Palb2 ISORGD:288761059068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 1

PMID:25741868
Palb2 ISORGD:85913289068941ClinVarClinVar Annotator: match by term: Breast and/or ovarian cancer

PMID:17200668, PMID:18302019, PMID:21365267, PMID:21618343, PMID:22052327, PMID:23935836, PMID:24556926, PMID:24949998, PMID:25741868, PMID:26283626, PMID:26467025, PMID:26564480, PMID:27573125, PMID:28492532
Palb2 ISORGD:85913659068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:21285249, PMID:21409391, PMID:23448497, PMID:24206657, PMID:25099575, PMID:25525159, PMID:25741868, PMID:26283626, PMID:26467025, PMID:26534844, PMID:26786923, PMID:27878467, PMID:28492532
Palb2 ISORGD:85914189068941ClinVarClinVar Annotator: match by term: Breast and/or ovarian cancer

PMID:17200668, PMID:18302019, PMID:19635604, PMID:20582465, PMID:20722467, PMID:21165770, PMID:21365267, PMID:21618343, PMID:22241545, PMID:23824750, PMID:23935836, PMID:24033266, PMID:24141787, PMID:24448499, PMID:24556926, PMID:24949998, PMID:25186627, PMID:25356972, PMID:25479140, PMID:25575445, PMID:25741868, PMID:26094658, PMID:26283626, PMID:26315354, PMID:26467025, PMID:26534844, PMID:26564480, PMID:26740942, PMID:27099641, PMID:27153395, PMID:27328445, PMID:27397723, PMID:27573125, PMID:27595995, PMID:27829436, PMID:28492532
Palb2 ISORGD:85914319068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:17420451, PMID:21285249, PMID:24870022, PMID:25099575, PMID:26681312, PMID:26898890, PMID:28492532, PMID:28779002
Palb2 ISORGD:85914439068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:21285249, PMID:22241545, PMID:23977390, PMID:25575445, PMID:25741868, PMID:26283626, PMID:26411315, PMID:26467025, PMID:26489409, PMID:26692951, PMID:27616075, PMID:27783279, PMID:28492532, PMID:28580595, PMID:28664506, PMID:28825143, PMID:30287823
Palb2 ISORGD:85914469068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:17200668, PMID:18302019, PMID:19264984, PMID:21182766, PMID:21285249, PMID:21409391, PMID:22241545, PMID:23448497, PMID:23471749, PMID:23787919, PMID:24206657, PMID:24415441, PMID:25099575, PMID:25225577, PMID:25356972, PMID:25575445, PMID:25741868, PMID:26283626, PMID:26315354, PMID:26467025, PMID:26534844, PMID:26845104, PMID:28492532, PMID:28864920, PMID:29431189
Palb2 ISORGD:85914649068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:19264984, PMID:23561644, PMID:25356972, PMID:25741868, PMID:26283626, PMID:26315354, PMID:26681312, PMID:26720728, PMID:26845104, PMID:28492532, PMID:28724667, PMID:29752822
Palb2 ISORGD:85914679068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:21285249, PMID:24082139, PMID:25741868, PMID:25980754, PMID:26283626, PMID:26467025, PMID:27783279, PMID:28492532, PMID:30287823
Palb2 ISORGD:85914699068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 1

PMID:17200671, PMID:19584259, PMID:19609323, PMID:21165770, PMID:23341105, PMID:25099575, PMID:25452441, PMID:25741868, PMID:26467025, PMID:26845104, PMID:28281021, PMID:28492532
Palb2 ISORGD:86585439068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:20412113, PMID:21165770, PMID:21285249, PMID:21618343, PMID:22692731, PMID:24136930, PMID:24448499, PMID:25099575, PMID:25186627, PMID:25741868, PMID:26467025, PMID:26681312, PMID:27553368, PMID:28492532, PMID:28528518, PMID:29470806, PMID:30067863
Palb2 ISORGD:86585589068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 2

PMID:24728327, PMID:25741868, PMID:26411315, PMID:27783279, PMID:28380452, PMID:28492532, PMID:28796317, PMID:29190888, PMID:30287823
Palb2 ISORGD:86585699068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 2

PMID:17200668, PMID:17200671, PMID:19264984, PMID:19584259, PMID:19609323, PMID:20927582, PMID:21165770, PMID:21365267, PMID:25099575, PMID:25741868, PMID:26283626, PMID:26296701, PMID:26315354, PMID:26467025, PMID:26641009, PMID:26681312, PMID:28492532
Palb2 ISORGD:86899179068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 1

PMID:24033266, PMID:24448499, PMID:24556926, PMID:25099575, PMID:25741868, PMID:26315354, PMID:26467025, PMID:26845104, PMID:27624329, PMID:28492532
Palb2 ISORGD:86971389068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868, PMID:28492532, PMID:30287823
Palb2 ISORGD:86980139068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:17200671, PMID:19264984, PMID:19763884, PMID:20852946, PMID:21618343, PMID:24033266, PMID:25099575, PMID:25186627, PMID:25452441, PMID:25741868, PMID:26467025, PMID:27783279, PMID:27798748, PMID:28152038, PMID:28423363, PMID:28486781, PMID:28492532, PMID:28724667, PMID:28779002, PMID:29338689, PMID:29566657, PMID:29752822, PMID:29915322, PMID:30287823, PMID:31300551
Palb2 ISORGD:98346809068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:23977390, PMID:25186627, PMID:25741868, PMID:26283626, PMID:26411315, PMID:26467025, PMID:26692951, PMID:27783279, PMID:28492532, PMID:28580595, PMID:28767289, PMID:28825143, PMID:30287823
Palb2 ISORGD:98515449068941ClinVarClinVar Annotator: match by term: Breast-ovarian cancer, familial 2

PMID:25741868, PMID:26283626, PMID:26315354, PMID:26411315, PMID:26689913, PMID:27621404, PMID:28492532, PMID:28796317, PMID:29667044, PMID:29802286, PMID:30287823
Palb2 ISORGD:98539779068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:25741868, PMID:26411315, PMID:28492532, PMID:28796317, PMID:30287823
Palb2 ISORGD:98542489068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:27878467
Palb2 ISORGD:98543939068941ClinVarClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome

PMID:17200668, PMID:25099575, PMID:25741868, PMID:28492532
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.