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GENE - TERM ANNOTATION REPORT

CRRD ID: 9020692
Species: Chinchilla lanigera
CRRD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: DOID:11247
Term: disseminated intravascular coagulation
Definition: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
Definition Source(s): MESH:D004211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3 ISORGD:25879068941CRRDmRNA, protein:increased expression:lung, plasma

PMID:9426395, REF_RGD_ID:11060265
F3 ISORGD:7373549068941CRRDassociated with Leukemia, Myeloid

PMID:3802033, REF_RGD_ID:11341675
F3 ISORGD:7373549068941CRRDprotein:increased expression:plasma

PMID:8914465, REF_RGD_ID:11060253
F3 ISORGD:7373549068941CTDCTD Direct Evidence: marker/mechanism

PMID:20642682, PMID:7740478, PMID:9134660
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.