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GENE - TERM ANNOTATION REPORT

CRRD ID: 9020692
Species: Chinchilla lanigera
CRRD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: PW:0000474
Term: coagulation cascade pathway
Definition: The coagulation cascade is the series of events proceeding via the tissue factor (extrinsic) or the contact activation (intrinsic) pathway and converging in the formation of fibrin clots. Several anticoagulation systems are in place to modulate the pathway. The coagulation cascade and the complement pathway of immune responses are connected in a cross talk.
Definition Source(s): PMID:26018600, PMID:26149013
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.