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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1352441
Species: Homo sapiens
CRRD Object: Gene
Symbol: GPRC6A
Name: G protein-coupled receptor class C group 6 member A
Acc ID: CHEBI:10033
Term: warfarin
Definition: A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.
Chemical ID: MESH:D014859
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7350776480464CTDWarfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA]

PMID:27488359
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.