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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1566119
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: H2ax
Name: H2A.X variant histone
Acc ID: CHEBI:10138
Term: [6]-Shogaol
Definition: A monomethoxybenzene that has formula C17H24O3.
Chemical ID: MESH:C040115
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2axmultiple interactionsISORGD:13464646480464CTDshogaol analog inhibits the reaction [Doxorubicin results in increased phosphorylation of H2AX protein]

PMID:23899529
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.