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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621032
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nr0b2
Name: nuclear receptor subfamily 0, group B, member 2
Acc ID: CHEBI:135338
Term: guggulsterone
Definition: null
Chemical ID: MESH:C023617
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7328736480464CTDpregna-4, 17-diene-3, 16-dione inhibits the reaction [Imatinib Mesylate results in increased expression of NR0B2 mRNA]

PMID:22414727
multiple interactionsISORGD:7328746480464CTDpregna-4, 17-diene-3, 16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of NR0B2 mRNA]]

PMID:25655198
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.