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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1311509
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ercc6
Name: ERCC excision repair 6, chromatin remodeling factor
Acc ID: CHEBI:15351
Term: acetyl-CoA
Definition: An acyl-CoA having acetyl as its S-acetyl component.
Chemical ID: MESH:D000105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases abundanceISOCRRD:13230056480464CTDERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A

PMID:25440059
multiple interactionsISOCRRD:13230056480464CTD3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]

N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]

PMID:25440059
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.