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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737494
Species: Homo sapiens
CRRD Object: Gene
Symbol: SYP
Name: synaptophysin
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDTretinoin results in increased expression of SYP mRNA

PMID:23903816
multiple interactionsEXP 6480464CTD[Tretinoin co-treated with SHH protein co-treated with FGF8 protein] results in increased expression of SYP protein

PMID:17085092
increases expressionISORGD:113736480464CTDTretinoin results in increased expression of SYP mRNA

PMID:20865013
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.