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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730858
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL2
Name: interleukin 2
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases secretionEXP 6480464CTDAcrolein results in decreased secretion of IL2 protein

PMID:17491020
multiple interactionsEXP 6480464CTDAcrolein inhibits the reaction [NFKB1 protein binds to IL2 promoter]

PMID:17491020
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.