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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 732955
Species: Mus musculus
CRRD Object: Gene
Symbol: Dusp1
Name: dual specificity phosphatase 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:6208976480464CTDOxygen deficiency results in increased expression of DUSP1 mRNA, Oxygen deficiency results in increased expression of DUSP1 protein

PMID:11577072
increases expressionISORGD:7329546480464CTDOxygen deficiency results in increased expression of DUSP1 mRNA, Oxygen deficiency results in increased expression of DUSP1 protein

PMID:11577072, PMID:24236059, PMID:24267255, PMID:26516004
multiple interactionsISORGD:6208976480464CTDSB 203580 inhibits the reaction [Oxygen deficiency results in increased expression of DUSP1 mRNA]

PMID:11577072
multiple interactionsISORGD:7329546480464CTDDUSP1 mutant form inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]

PMID:24267255
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.