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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737062
Species: Homo sapiens
CRRD Object: Gene
Symbol: PRKCA
Name: protein kinase C alpha
Acc ID: CHEBI:16118
Term: berberine
Definition: A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID: MESH:D001599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:33956480464CTDarsenic trioxide promotes the reaction [Berberine results in decreased activity of PRKCA protein], Berberine results in decreased activity of and affects the localization of PRKCA protein

PMID:18294404
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.