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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3382
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ppp3ca
Name: protein phosphatase 3 catalytic subunit alpha
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDEthanol results in decreased expression of PPP3CA mRNA

PMID:20655511
affects splicingISORGD:111346480464CTDEthanol affects the splicing of PPP3CA mRNA

PMID:30319688
increases expressionISORGD:111346480464CTDEthanol results in increased expression of PPP3CA protein

PMID:19332462
multiple interactionsISORGD:111346480464CTDALDH2 protein inhibits the reaction [Ethanol results in increased expression of PPP3CA protein]

PMID:19332462
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.