Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 628843
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mfn2
Name: mitofusin 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects splicingISOCRRD:7325706480464CTDEthanol affects the splicing of MFN2 mRNA

PMID:30319688
increases degradationISOCRRD:7325706480464CTDEthanol results in increased degradation of MFN2 protein

PMID:25460735
multiple interactionsISOCRRD:7325706480464CTDNR1H4 gene mutant form inhibits the reaction [Ethanol results in increased degradation of MFN2 protein]

PMID:25460735
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.