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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620800
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Bnip3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:13509136480464CTDHydrogen Peroxide affects the expression of BNIP3 mRNA

PMID:20044591
decreases expressionISORGD:13509136480464CTDHydrogen Peroxide results in decreased expression of BNIP3 mRNA, Hydrogen Peroxide results in decreased expression of BNIP3 protein

PMID:12419474, PMID:29061316, PMID:30316844
multiple interactionsISORGD:13509136480464CTD[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 protein], ARNTL protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 protein]], ARNTL protein affects the reaction [Polyphenols inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 mRNA]], Polyphenols inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 mRNA]

PMID:29061316, PMID:30316844
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.