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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 732955
Species: Mus musculus
CRRD Object: Gene
Symbol: Dusp1
Name: dual specificity phosphatase 1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDHydrogen Peroxide results in increased expression of DUSP1 mRNA

PMID:11689710
multiple interactionsEXP 6480464CTDU 0126 inhibits the reaction [Hydrogen Peroxide results in increased expression of DUSP1 mRNA]

PMID:11689710
affects expressionISORGD:7329546480464CTDHydrogen Peroxide affects the expression of DUSP1 mRNA

PMID:20044591, PMID:23410634
increases expressionISORGD:7329546480464CTDHydrogen Peroxide results in increased expression of DUSP1

PMID:18687144
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.