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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621543
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases phosphorylationISORGD:7328626480464CTDQuercetin results in increased phosphorylation of CHEK2 protein

PMID:24595819
multiple interactionsISORGD:7328616480464CTDQuercetin results in increased phosphorylation of and results in increased activity of CHEK2 protein

PMID:19009557
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