Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 70913
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Abcc5
Name: ATP binding cassette subfamily C member 5
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases response to substanceISORGD:7343636480464CTDABCC5 protein results in decreased susceptibility to Quercetin

PMID:16156793
multiple interactionsISORGD:7343636480464CTDQuercetin inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine], Quercetin inhibits the reaction [ABCC5 protein results in increased export of 2', 7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]

PMID:16156793
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.