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CRRD ID: 1561030
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Deptor
Name: DEP domain containing MTOR-interacting protein
Acc ID: CHEBI:16330
Term: 17beta-hydroxy-5alpha-androstan-3-one
Definition: A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5.
Chemical ID: MESH:D013196
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13442616480464CTDDihydrotestosterone results in decreased expression of DEPTOR mRNA, Dihydrotestosterone results in decreased expression of DEPTOR protein

multiple interactionsISORGD:13442616480464CTDbicalutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of DEPTOR mRNA]

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.