GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1305950
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mybpc3
Name: myosin binding protein C, cardiac
Acc ID: CHEBI:164200
Term: triclosan
Definition: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Chemical ID: MESH:D014260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:13142846480464CTDTriclosan results in decreased expression of MYBPC3 mRNA

PMID:30510588
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.