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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 71090
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gatm
Name: glycine amidinotransferase
Acc ID: CHEBI:164200
Term: triclosan
Definition: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Chemical ID: MESH:D014260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7319366480464CTDTriclosan results in decreased expression of GATM mRNA

PMID:30510588
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.