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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1309603
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Csta
Name: cystatin A
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13200296480464CTDEstradiol results in decreased expression of CSTA mRNA

PMID:15072547
increases expressionISORGD:13200296480464CTDEstradiol results in increased expression of CSTA mRNA

PMID:19619570, PMID:20106945, PMID:21632981
multiple interactionsISORGD:13200296480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CSTA mRNA, [Estradiol co-treated with TGFB1 protein] results in decreased expression of CSTA mRNA

PMID:19619570, PMID:30165855
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.