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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1315197
Species: Homo sapiens
CRRD Object: Gene
Symbol: DHCR24
Name: 24-dehydrocholesterol reductase
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDEstradiol results in decreased expression of DHCR24 mRNA

PMID:18260696, PMID:23373633
increases expressionEXP 6480464CTDEstradiol results in increased expression of DHCR24 mRNA

PMID:15585566
increases expressionISORGD:13151986480464CTDEstradiol results in increased expression of DHCR24 mRNA

PMID:20826375
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.