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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1557049
Species: Mus musculus
CRRD Object: Gene
Symbol: Slitrk4
Name: SLIT and NTRK-like family, member 4
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13485826480464CTD[Estradiol binds to ESR2 protein] which results in increased expression of SLITRK4 mRNA, [Estradiol co-treated with Progesterone] results in decreased expression of SLITRK4 mRNA

PMID:20404318, PMID:20660070
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.