Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


CRRD ID: 1583909
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Dhrs2
Name: dehydrogenase/reductase 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13217746480464CTDEstradiol results in increased expression of DHRS2 mRNA

PMID:16474171, PMID:19619570, PMID:21185374
multiple interactionsISORGD:13217746480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DHRS2 mRNA, [Estradiol co-treated with TGFB1 protein] results in increased expression of DHRS2 mRNA, Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of DHRS2 mRNA]

PMID:19619570, PMID:21185374, PMID:30165855
Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.