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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621612
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nts
Name: neurotensin
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDEstradiol results in increased expression of NTS mRNA

PMID:20068009
increases expressionISORGD:13190926480464CTDEstradiol results in increased expression of NTS mRNA

PMID:21795739
multiple interactionsISORGD:13190926480464CTD[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NTS mRNA, Progesterone inhibits the reaction [Estradiol results in increased expression of NTS mRNA]

PMID:20823114, PMID:21795739
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.