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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621821
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Fen1
Name: flap structure-specific endonuclease 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7326806480464CTDEstradiol affects the expression of FEN1 mRNA

PMID:15598610
increases expressionISORGD:7326796480464CTDEstradiol results in increased expression of FEN1 mRNA

PMID:16474171, PMID:19167446
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.