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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 68393
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Kcnd2
Name: potassium voltage-gated channel subfamily D member 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of KCND2 mRNA

PMID:26496021
decreases expressionISORGD:685756480464CTDEstradiol results in decreased expression of KCND2 mRNA

PMID:19484750
multiple interactionsISORGD:685746480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of KCND2 mRNA

PMID:20660070
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.