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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69152
Species: Homo sapiens
CRRD Object: Gene
Symbol: EGFR
Name: epidermal growth factor receptor
Acc ID: CHEBI:16482
Term: naphthalene
Definition: An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia.
Chemical ID: MESH:C031721
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:105116480464CTD[gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene

PMID:20935109
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.