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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1323510
Species: Mus musculus
CRRD Object: Gene
Symbol: Akr1c21
Name: aldo-keto reductase family 1, member C21
Acc ID: CHEBI:16486
Term: cyclopentanone
Definition: A cyclic ketone that consists of cyclopentane bearing a single oxo substituent.
Chemical ID: MESH:C007201
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases reductionISORGD:13539016480464CTDAKR1C2 protein results in increased reduction of cyclopentanone

PMID:23261716
multiple interactionsISORGD:13539016480464CTD[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone, NADP promotes the reaction [AKR1C2 protein results in increased reduction of cyclopentanone], Ursodeoxycholic Acid inhibits the reaction [[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone]

PMID:23261716
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.