GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1311841
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Akr1c2
Name: aldo-keto reductase family 1, member C2
Acc ID: CHEBI:16509
Term: 1,4-benzoquinone
Definition: The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
Chemical ID: MESH:C004532
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:13539016480464CTDquinone results in increased expression of AKR1C2 mRNA

PMID:20491607
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.