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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3281
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Pde4d
Name: phosphodiesterase 4D
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases methylationEXP 6480464CTDTrichloroethylene results in increased methylation of PDE4D gene

PMID:27618143
increases expressionISOCRRD:110666480464CTDTrichloroethylene results in increased expression of PDE4D mRNA

PMID:25549359
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