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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621642
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:15517136480464CTDPPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of TIE1 mRNA]

PMID:15363585
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.