GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621409
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Pls3
Name: plastin 3
Acc ID: CHEBI:16716
Term: benzene
Definition: A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system.
Chemical ID: MESH:D001554
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of PLS3 mRNA

PMID:17905399
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.