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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 68370
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tdo2
Name: tryptophan 2,3-dioxygenase
Acc ID: CHEBI:16827
Term: corticosterone
Definition: A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Chemical ID: MESH:D003345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTDCorticosterone results in increased activity of TDO2 protein

PMID:7306070
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