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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730858
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL2
Name: interleukin 2
Acc ID: CHEBI:16980
Term: geranial
Definition: A monoterpenoid that is (2E,6E)-octa-2,6-dienal substituted by methyl groups at positions 3 and 7.
Chemical ID: MESH:C007076
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA

PMID:29594315
increases secretionISORGD:7333156480464CTDcitral results in increased secretion of IL2 protein

PMID:22245253
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.