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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3772
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Stat3
Name: signal transducer and activator of transcription 3
Acc ID: CHEBI:17029
Term: chitin
Definition: An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
Chemical ID: MESH:D002686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat3multiple interactionsISORGD:7375176480464CTD[[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA], [Docetaxel binds to Chitin] which results in decreased expression of STAT3 mRNA, [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA

PMID:30041514
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.