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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2081
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:17033
Term: biliverdin
Definition: A linear tetrapyrrole produced in the reticuloendothelial system by the first step of heme degradation, catalysed by heme oxygenase.
Chemical ID: MESH:D001664
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1multiple interactionsISORGD:7329096480464CTDBiliverdine inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein]

PMID:18215737
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.