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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2275
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:17033
Term: biliverdin
Definition: A linear tetrapyrrole produced in the reticuloendothelial system by the first step of heme degradation, catalysed by heme oxygenase.
Chemical ID: MESH:D001664
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISORGD:102896480464CTD[Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein], Biliverdine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]

PMID:15486963
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.