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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2465
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp2a3
Name: cytochrome P450, family 2, subfamily a, polypeptide 3
Acc ID: CHEBI:17033
Term: biliverdin
Definition: A linear tetrapyrrole produced in the reticuloendothelial system by the first step of heme degradation, catalysed by heme oxygenase.
Chemical ID: MESH:D001664
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2a3increases chemical synthesisISORGD:7318676480464CTDCYP2A5 protein results in increased chemical synthesis of Biliverdine

PMID:21871474
Cyp2a3multiple interactionsISORGD:7318676480464CTD[CYP2A5 protein results in increased oxidation of Bilirubin] which results in increased chemical synthesis of Biliverdine

PMID:21871474
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.