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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2139
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:17189
Term: 2,5-dihydroxybenzoic acid
Definition: A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.
Chemical ID: MESH:C010925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appmultiple interactionsISORGD:7360216480464CTD2, 5-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form], Gallic Acid inhibits the reaction [2, 5-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]]

PMID:22129351
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.