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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2645
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:17189
Term: 2,5-dihydroxybenzoic acid
Definition: A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.
Chemical ID: MESH:C010925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pddecreases activityISORGD:7364746480464CTD2, 5-dihydroxybenzoic acid results in decreased activity of G6PD protein mutant form

PMID:5432368
G6pdmultiple interactionsISORGD:106086480464CTD2, 5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]

PMID:15454305
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.