GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2874
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
Acc ID: CHEBI:17315
Term: D-glucosamine
Definition: An amino sugar whose structure comprises D-glucose having an amino substituent at position 2.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDGlucosamine results in decreased expression of IGFBP3 mRNA

PMID:17109745
multiple interactionsEXP 6480464CTDGlucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]

IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]

PMID:17109745
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.